We provide specialized bioinformatic services to advance your technological and scientific goals



Tim Fennell

Tim Fennell
Founding Partner

Tim Fennell is a Founding Partner at Fulcrum Genomics LLC, with over a decade of experience in genomics and bioinformatics.  He combines a background in computer science and large-scale software engineering with a passion for molecular biology, genetics, and statistics in order to rapidly solve challenging problems in genomics.  Prior to founding Fulcrum Genomics, Tim served as Director of Bioinformatics at the Broad Institute where he led the development and operation of pipelines for the institute's Next Generation Sequencing (NGS) data, the bioinformatics strategy for the creation of a CLIA licensed clinical sequencing lab, and was the lead author of the industry standard Picard suite of programs for working with NGS data.  Before moving into the life sciences, Tim was a business and technology consultant at Sapient Corporation where he developed innovative process and technological solutions to solve business challenges for clients in the Energy Services, Financial Services and Healthcare industries.

Nils Homer

Nils Homer
Founding Partner

Nils Homer is a Founding Partner at Fulcrum Genomics LLC and has over a decade of cutting-edge experience developing methods and software for the analysis of next-generation sequencing data.  He has led high-pace technology and product development efforts at both industry and academic positions, and has directed teams of software developers to support the largest academic genome sequencing facility in the world for both research and clinical applications. Nils has also participated in the technology development and subsequent commercial launch of multiple sequencing assays and technologies, providing critical understanding for technical improvements in chemistry, molecular biology, and software. He combines his skill in developing novel methods, algorithms, and software with his understanding of the data produced to provide key insights into biological research and discovery.  Nils holds a Masters and PhD in Computer Science from UCLA investigating methods applied to genomics, including alignment and variant detection for whole genome sequencing. He received his BA (Computer Science and Mathematics) from Colgate University. Nils currently serves on the Scientific Advisory Board for Edico Genome.


Our founders each have over a decade of experience in genomic analysis from small startups to the largest sequencing centers in the world.


We have built widely used bioinformatic tools, as well as clinical and research pipelines, supporting custom analyses and large scale sequencing centers.


We solve complex bioinformatics problems from signal processing through biological interpretation, providing expertise in experimental design through to critical metrics and final results.


Founded in August of 2015, Fulcrum Genomics LLC provides specialized bioinformatic services to advance technology and the understanding of human disease.  Utilizing our extensive experience in both industry and academia, and in research and clinical settings, we adapt tools and pipelines to suit your needs.  We have extensive experience from designing assays for target capture, including solution-based as well as multiplex PCR.   We have participated in developing novel sequencing technologies and assays, from signal processing through primary analysis and finally interpretation, while providing critical insight into upstream improvements in laboratory preparation.  We have built and operated analysis pipelines to support the most high-through genomic production environments, managing the analysis and storage of petabytes of data, along with critical laboratory and phenotypic metadata, both in research and CLIA licensed environments.  We strive to understand your problems and provide solutions that you can use to improve your research and product development or for your technology and assay.

Let us help you focus on your strengths by providing our vision, strategy, and experience in bioinformatics and genomics.